Search Results - diagnosis

11 Results Sort By:
­AUTOANTIBODIES AS BIOMARKERS FOR LIPODYSTROPHY
­AUTOANTIBODIES AS BIOMARKERS FOR LIPODYSTROPHY Researchers at UCSF and the Chan Zuckerberg Biohub have developed methods to identify a subject that is at risk of developing autoimmune-related lipodystrophy. Lipodystrophy is a clinical phenotype defined by a reduction in subcutaneous fat or adipose tissue. Excessive fat loss can lead to an imbalance...
Published: 8/15/2022   |   Inventor(s): Caleigh Mandel-Brehm, Joseph DeRisi, Mark Anderson
Keywords(s): Antibody, Autoantibody, Autoimmune, Biomolecules, Diagnosis, IgG, Immunotherapy, Lipodystrophy
Category(s): Technology Classifications > Biology
­NUCLEIC ACID SEQUENCE DETECTION BY MEASURING FREE MONORIBONUCLEOTIDES GENERATED BY ENDONUCLEASE COLLATERAL CLEAVAGE ACTIVITY
­NUCLEIC ACID SEQUENCE DETECTION BY MEASURING FREE MONORIBONUCLEOTIDES GENERATED BY ENDONUCLEASE COLLATERAL CLEAVAGE ACTIVITY Researchers at the Chan Zuckerberg Biohub have developed an improved method to detect target nucleic acid sequences in a biological sample, NANCI™. CRISPR-associated protein (Cas) technology is a sequence-specific...
Published: 5/19/2022   |   Inventor(s): Emily Crawford, Amy Lyden
Keywords(s): Biomolecules, Biosensor System, CRISPR, Diagnosis, Nuclease
Category(s): Technology Classifications > Biology
­METHODS FOR PREDICTING THE RESPONSE TO METHOTREXATE AND TREATING RHEUMATOID ARTHRITIS
­METHODS FOR PREDICTING THE RESPONSE TO METHOTREXATE AND TREATING RHEUMATOID ARTHRITIS Researchers at UCSF have developed methods of treating Rheumatoid arthritis and for predicting the response of patients to methotrexate. Rheumatoid arthritis (RA) is an autoimmune disease that leads to inflammation and destruction of joints, as well as other...
Published: 1/14/2022   |   Inventor(s): Renuka Nayak, Peter Turnbaugh
Keywords(s): Diagnosis, Immunotherapy
Category(s): Technology Classifications > Biology
AUTOANTIBODIES AS BIOMARKERS FOR AUTOIMMUNE POLYGLANDULAR SYNDROME TYPE 1
AUTOANTIBODIES AS BIOMARKERS FOR AUTOIMMUNE POLYGLANDULAR SYNDROME TYPE 1 Researchers at UCSF and the Chan Zuckerberg Biohub have identified multiple common autoantibody targets in APS1 patients through proteome-wide programmable phage-display. The identification of autoantigens remains a critical challenge for understanding and treating autoimmune...
Published: 1/14/2022   |   Inventor(s): Sara Vazquez, Mark Anderson, Joseph DeRisi
Keywords(s): Antibody, Autoantibody, Diagnosis, Particle Display, Serum
Category(s): Technology Classifications > Biology
­POINT-OF-CARE AND IMPROVED DETECTION AND QUANTIFICATION OF BIOMOLECULES
­POINT-OF-CARE AND IMPROVED DETECTION AND QUANTIFICATION OF BIOMOLECULES Researchers at UCSF and the Chan Zuckerberg Biohub have developed a workflow for accurate bulk quantitation of droplet digital PCR, which can be used in point-of-care clinical settings with minimal sample processing. The quantitation of nucleic acids is important for clinical...
Published: 10/26/2021   |   Inventor(s): Adam Abate, Xiangpeng Li
Keywords(s): Biomolecules, Diagnosis, Droplet Digital PCR, Fluorescence, High-Throughput, Microfluidics, SARS-CoV-2
Category(s): Technology Classifications > Biology
METHODS, COMPOSITIONS, AND KITS FOR ASSESSING ENDOMETRIAL TRANSFORMATION
METHODS, COMPOSITIONS, AND KITS FOR ASSESSING ENDOMETRIAL TRANSFORMATION Researchers at Stanford and the Chan Zuckerberg Biohub have developed a transcriptomic characterization of human endometrium and identified specific gene signatures for use in evaluating endometrial samples for one or more menstrual cycle events. In a human menstrual cycle,...
Published: 8/12/2021   |   Inventor(s): Stephen Quake, Carlos Simon, Wanxin Wang, Felipe Viella
Keywords(s): Diagnosis, Single Cell, Single Cell RNA Sequencing, Single-cell Transcriptomics
Category(s): Technology Classifications > Biology
PREDICTION OF PREECLAMPSIA RISK USING CIRCULATING CELL-FREE RNA
PREDICTION OF PREECLAMPSIA RISK USING CIRCULATING CELL-FREE RNA Researchers at Stanford and the Chan Zuckerberg Biohub have developed methods for predicting the risk or existence of preeclampsia. Preeclampsia, a multi-organ syndrome diagnosed after 20 weeks of gestation, is associated with an increase in adverse maternal and perinatal outcomes. Detection...
Published: 6/24/2021   |   Inventor(s): Stephen Quake, Gary Shaw, David Stevenson, Mira Moufarrej
Keywords(s): cfRNA, Diagnosis, Gestational Age, Machine Learning, Maternal Blood, Maternal Plasma
Category(s): Technology Classifications > Biology
BIOSENSOR DETECTION ASSAY FOR ANTI-SARS-COV-2 ANTIBODIES
BIOSENSOR DETECTION ASSAY FOR ANTI-SARS-COV-2 ANTIBODIES Researchers at UCSF and the Chan Zuckerberg Biohub have developed a serological detection assay for anti-SARS-CoV-2 antibodies. COVID-19, caused by the SARS-CoV-2 virus, has spread throughout the world. Early detection of disease using viral detection assays is critical for containing the spread...
Published: 4/16/2021   |   Inventor(s): James Wells, Susanna Elledge, Xin Zhou
Keywords(s): Antibody, Biosensor System, Diagnosis, Epitope Shield, IgG
Category(s): Technology Classifications > Biology
DETECTION ASSAY FOR SARS-COV-2 VIRUS
DETECTION ASSAY FOR SARS-COV-2 VIRUS Researchers at UCSF and the Chan Zuckerberg Biohub have developed methods to detect SARS-CoV-2 virus. Clinical laboratory tests and point-of-care tests are needed for screening and diagnosis of individuals infected with SARS-CoV-2 virus. SARS-CoV-2 infection begins with viral Spike protein binding to the human...
Published: 4/16/2021   |   Inventor(s): James Wells, Susanna Elledge, Xin Zhou, Tanja Kortemme, Jeff Glasgow, Anum Glasgow, Irene Lui
Keywords(s): Affinity Reagent, Antibody, Biosensor System, Diagnosis, Fc Domain
Category(s): Technology Classifications > Biology
MULTIPLEXED DETECTION AND CHARACTERIZATION OF MICROBIAL NUCLEIC ACIDS USING SPECTRALLY ENCODED BEADS
MULTIPLEXED DETECTION AND CHARACTERIZATION OF MICROBIAL NUCLEIC ACIDS USING SPECTRALLY ENCODED BEADS Researchers at Stanford and the Chan Zuckerberg Biohub have developed a platform for characterizing a population of microbes using spectrally encoded beads. The clinical treatment of microbial infections is dependent on the proper identification and...
Published: 2/11/2021   |   Inventor(s): Adam White, Huy Nguyen, Feiqiao Yu, Tyler Shimko, Polly Fordyce, Nadya Andini, Samuel Yang
Keywords(s): Blood, Diagnosis, Fluorescence, Microbe, Microfluidics, Nucleic Acid, RNA-seq
Category(s): Technology Classifications > Biology
1 2