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NUCLEIC ACID SEQUENCE DETECTION BY MEASURING FREE MONORIBONUCLEOTIDES GENERATED BY ENDONUCLEASE COLLATERAL CLEAVAGE ACTIVITY
NUCLEIC ACID SEQUENCE DETECTION BY MEASURING FREE MONORIBONUCLEOTIDES GENERATED BY ENDONUCLEASE COLLATERAL CLEAVAGE ACTIVITY
Researchers at the Chan Zuckerberg Biohub have developed an improved method to detect target nucleic acid sequences in a biological sample, NANCI™.
CRISPR-associated protein (Cas) technology is a sequence-specific...
Published: 3/17/2023
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Inventor(s): Emily Crawford, Amy Lyden
Keywords(s): Biomolecules, Biosensor System, CRISPR, Diagnosis, Nuclease
Category(s): Technology Classifications > Biology
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FLASH-MS: FINDING LOW ABUNDANCE SEQUENCES BY CAS9 HYBRIDIZATION MASS SPECTROMETRY
FLASH-MS: FINDING LOW ABUNDANCE SEQUENCES BY CAS9 HYBRIDIZATION MASS SPECTROMETRY
Researchers at the Chan Zuckerberg Biohub have developed FLASH-MS, a method for nucleic acid sequence detection by endonuclease digestion and mass spectrometry.
The rapid detection of low abundance targets from clinical specimens is a central challenge in clinical diagnostics....
Published: 3/17/2023
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Inventor(s): Emily Crawford
Keywords(s): Cas9, CRISPR, Genome Dissection, Nuclease, RNA Sequencing
Category(s): Technology Classifications > Biology
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FLASH (FINDING LOW ABUNDANCE SEQUENCES BY HYBRIDIZATION)
FLASH (FINDING LOW ABUNDANCE SEQUENCES BY HYBRIDIZATION)
Researchers at the Chan Zuckerberg Biohub have developed an improved technique, FLASH, which uses a programmable nuclease to enrich target sequences during preparation of nucleotide libraries.
Next generation sequencing (NGS) technology is a powerful tool in diagnostic and functional genomics....
Published: 3/17/2023
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Inventor(s): Emily Crawford, Jenai Quan
Keywords(s): Cas9, CRISPR, Multiplex PCR, Next Generation Sequencing (NGS), Nucleic Acid Library
Category(s): Technology Classifications > Biology
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