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SPATIAL GENOMICS WITH SINGLE CELL RESOLUTION
SPATIAL GENOMICS WITH SINGLE CELL RESOLUTION
Researchers at UCSF have developed methods for in situ labelling and sequencing to obtain spatial information and multiomics analysis at a single cell level.
Single-cell sequencing has revealed unappreciated cellular diversity in many ostensibly homogeneous systems and led to an ongoing scientific...
Published: 7/5/2023
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Inventor(s): Cyrille Delley, Adam Abate
Keywords(s): Single Cell, Single Cell Analysis, Single Cell Genomics, Single Cell RNA Sequencing, Single-cell Transcriptomics
Category(s): Technology Classifications > Biology
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QUANTIFICATION OF CELLULAR PROTEINS USING BARCODED BINDING MOIETIES
QUANTIFICATION OF CELLULAR PROTEINS USING BARCODED BINDING MOIETIES
Researchers at Stanford have developed a method enabling quantification of intracellular protein levels using oligonucleotide-barcoded antibodies.
Multiplexing single cell technologies affords researchers the ability to characterize cell states and identify gene regulatory programs...
Published: 3/17/2023
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Inventor(s): William Greenleaf, Amy Chen
Keywords(s): Affinity Reagent, Antibody, Biomolecules, Integrated Screening System, ScRNA-seq, Single Cell, Single Cell Analysis, Single Cell Genomics, Single Cell RNA Sequencing, Single-cell Transcriptomics
Category(s): Technology Classifications > Biology
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MICROFLUIDIC CELL BARCODING AND SEQUENCING
MICROFLUIDIC CELL BARCODING AND SEQUENCING
Researchers at UC Berkeley have developed µCB-seq, a microfluidic cell barcoding and sequencing platform for high-resolution imaging and sequencing of single cells.
Single-cell RNA sequencing (scRNA-seq) enables the investigation of complex biological processes in multicellular organisms with high...
Published: 3/17/2023
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Inventor(s): Aaron Streets, Tyler Chen, Anushka Gupta
Keywords(s): Fluorescence, Genetic Dissection, Microfluidics, ScRNA-seq, Single Cell, Single Cell Analysis, Single Cell Genomics, Single Cell RNA Sequencing, Single-cell Transcriptomics
Category(s): Technology Classifications > Biology
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METHODS, COMPOSITIONS, AND KITS FOR ASSESSING ENDOMETRIAL TRANSFORMATION
METHODS, COMPOSITIONS, AND KITS FOR ASSESSING ENDOMETRIAL TRANSFORMATION
Researchers at Stanford and the Chan Zuckerberg Biohub have developed a transcriptomic characterization of human endometrium and identified specific gene signatures for use in evaluating endometrial samples for one or more menstrual cycle events.
In a human menstrual cycle,...
Published: 11/29/2023
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Inventor(s): Stephen Quake, Carlos Simon, Wanxin Wang, Felipe Viella
Keywords(s): Diagnosis, Single Cell, Single Cell RNA Sequencing, Single-cell Transcriptomics
Category(s): Technology Classifications > Biology
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BROADLY NEUTRALIZING ANTIBODIES AGAINST DENGUE VIRUS
BROADLY NEUTRALIZING ANTIBODIES AGAINST DENGUE VIRUS
Researchers at Stanford and the Chan Zuckerberg Biohub have discovered cross reactive, broadly neutralizing human antibodies against all serotypes of dengue virus.
Dengue virus (DENV) is transmitted to humans through mosquitos and causes approximately 400 million global infections each year. DENV...
Published: 3/17/2023
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Inventor(s): Fabio Zanini, Derek Croote, Makeda Robinson, Leslie Goo, Stephen Quake, Shirit Einav, Krista McCutcheon
Keywords(s): Broadly Neutralizing Antibodies (bNAbs), Dengue, Flavivirus, Monoclonal Antibodies (mAbs), Single-cell Transcriptomics, Vaccine
Category(s): Technology Classifications > Biology
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