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METHODS FOR GENERATING NUCLEIC ACID ENCODED PROTEIN LIBRARIES AND USES THEREOF
METHODS FOR GENERATING NUCLEIC ACID ENCODED PROTEIN LIBRARIES AND USES THEREOF
Researchers at UCSF have developed a new method for generating protein libraries encoded with nucleic acids for more efficient identification of molecular binders.
Basic biological principles dictate that form follows function. As such, protein-protein binding based on...
Published: 7/6/2023
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Inventor(s): Adam Abate, Cyrille Delley
Keywords(s): Binding Partners, Molecular Probe Libraries, Molecular Signature, Protein-Protein Interactions, Single Cell Sequencing
Category(s): Technology Classifications > Biology
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NUCLEAR DNA-ANTIBODY SEQUENCING FOR JOINT PROFILING OF GENOTYPE AND PROTEIN IN SINGLE NUCLEI
NUCLEAR DNA-ANTIBODY SEQUENCING FOR JOINT PROFILING OF GENOTYPE AND PROTEIN IN SINGLE NUCLEI
Researchers at UCSF have developed a method for joint nucleic acid-protein profiling from single nuclei that can be applied to all manner of biological samples, including frozen tumor specimens or infectious disease samples.
Cellular heterogeneity is an aspect...
Published: 5/18/2023
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Inventor(s): Harish Vasudevan, Benjamin Demaree, Cyrille Delley, Adam Abate
Keywords(s): Antibody, Frozen Specimens, Genotyping, Nuclei, Nucleic Acid, Phenotyping, Protein, Single Cell
Category(s): Technology Classifications > Biology
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SPATIAL GENOMICS WITH SINGLE CELL RESOLUTION
SPATIAL GENOMICS WITH SINGLE CELL RESOLUTION
Researchers at UCSF have developed methods for in situ labelling and sequencing to obtain spatial information and multiomics analysis at a single cell level.
Single-cell sequencing has revealed unappreciated cellular diversity in many ostensibly homogeneous systems and led to an ongoing scientific...
Published: 7/5/2023
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Inventor(s): Cyrille Delley, Adam Abate
Keywords(s): Single Cell, Single Cell Analysis, Single Cell Genomics, Single Cell RNA Sequencing, Single-cell Transcriptomics
Category(s): Technology Classifications > Biology
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