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MULTI-MODAL, SAME-CELL ASSAY FOR SEQUENCING AND PROTEIN DETECTION
Researchers at UC Berkeley have developed a platform that enables unified proteomic and nucleic acid-based omics analysis from the same cell.
Current multiplex assays, such as those relying on commercial systems like 10XGenomics, are limited in their ability to detect surface or intra-nuclear proteins and they require prior knowledge of target proteins...
Published: 10/23/2025
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Inventor(s): Amy Herr, Thi Thao Lam
Keywords(s): Multiplex, Nucleic Acid, Protein, Sequencing, Single Cell
Category(s): Technology Classifications > Biology
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NUCLEAR DNA-ANTIBODY SEQUENCING FOR JOINT PROFILING OF GENOTYPE AND PROTEIN IN SINGLE NUCLEI
NUCLEAR DNA-ANTIBODY SEQUENCING FOR JOINT PROFILING OF GENOTYPE AND PROTEIN IN SINGLE NUCLEI
Researchers at UCSF have developed a method for joint nucleic acid-protein profiling from single nuclei that can be applied to all manner of biological samples, including frozen tumor specimens or infectious disease samples.
Cellular heterogeneity is an aspect...
Published: 5/18/2023
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Inventor(s): Harish Vasudevan, Benjamin Demaree, Cyrille Delley, Adam Abate
Keywords(s): Antibody, Frozen Specimens, Genotyping, Nuclei, Nucleic Acid, Phenotyping, Protein, Single Cell
Category(s): Technology Classifications > Biology
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MULTIPLEXED DETECTION AND CHARACTERIZATION OF MICROBIAL NUCLEIC ACIDS USING SPECTRALLY ENCODED BEADS
MULTIPLEXED DETECTION AND CHARACTERIZATION OF MICROBIAL NUCLEIC ACIDS USING SPECTRALLY ENCODED BEADS
Researchers at Stanford and the Chan Zuckerberg Biohub have developed a platform for characterizing a population of microbes using spectrally encoded beads.
The clinical treatment of microbial infections is dependent on the proper identification and...
Published: 1/31/2025
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Inventor(s): Adam White, Huy Nguyen, Feiqiao Yu, Tyler Shimko, Polly Fordyce, Nadya Andini, Samuel Yang
Keywords(s): Blood, Diagnosis, Fluorescence, Microbe, Microfluidics, Nucleic Acid, RNA-seq
Category(s): Technology Classifications > Biology
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