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MULTI-MODAL, SAME-CELL ASSAY FOR SEQUENCING AND PROTEIN DETECTION
Researchers at UC Berkeley have developed a platform that enables unified proteomic and nucleic acid-based omics analysis from the same cell.
Current multiplex assays, such as those relying on commercial systems like 10XGenomics, are limited in their ability to detect surface or intra-nuclear proteins and they require prior knowledge of target proteins...
Published: 10/23/2025
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Inventor(s): Amy Herr, Thi Thao Lam
Keywords(s): Multiplex, Nucleic Acid, Protein, Sequencing, Single Cell
Category(s): Technology Classifications > Biology
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DROPLET-ELECTROPHORESIS DEVICES AND RELATED METHODS
DROPLET-ELECTROPHORESIS DEVICES AND RELATED METHODS
Researchers at UC Berkeley have developed a novel method for comprehensively profiling the proteomes of single cells.
Genomics (DNA) and transcriptomics (RNA) sequencing is one of the cornerstones of our modern-day understanding of the genetic blueprint of life. Furthermore, sequencing and...
Published: 4/22/2024
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Inventor(s): Amy Herr, Yang Liu
Keywords(s): Microfluidics, Protein, Single Cell Analysis
Category(s): Technology Classifications > Engineering
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NUCLEAR DNA-ANTIBODY SEQUENCING FOR JOINT PROFILING OF GENOTYPE AND PROTEIN IN SINGLE NUCLEI
NUCLEAR DNA-ANTIBODY SEQUENCING FOR JOINT PROFILING OF GENOTYPE AND PROTEIN IN SINGLE NUCLEI
Researchers at UCSF have developed a method for joint nucleic acid-protein profiling from single nuclei that can be applied to all manner of biological samples, including frozen tumor specimens or infectious disease samples.
Cellular heterogeneity is an aspect...
Published: 5/18/2023
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Inventor(s): Harish Vasudevan, Benjamin Demaree, Cyrille Delley, Adam Abate
Keywords(s): Antibody, Frozen Specimens, Genotyping, Nuclei, Nucleic Acid, Phenotyping, Protein, Single Cell
Category(s): Technology Classifications > Biology
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