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SINGLE-CELL CULTURE AND SEQUENCING WITH LIPID-MODIFIED OLIGOS

SINGLE-CELL CULTURE AND SEQUENCING WITH LIPID-MODIFIED OLIGOS Researchers at UCSF have developed methods for sequencing a single cell from a cell culture sample and obtaining morphologic or phenotypic measurements and information by combining sequencing approaches and spatial hashing (e.g. barcoding) at a single cell level. There exists a need in...

Published: 7/27/2023 | Inventor(s): Kai-Chun Chang, Adam Abate

Keywords(s): Lipid-Modified, Oligonucleotides, Sequencing, Single Cell

Category(s): Technology Classifications > Biology

PARTITIONING CELLS FOR HIGH-THROUGHPUT SINGLE-CELL SEQUENCING

PARTITIONING CELLS FOR HIGH-THROUGHPUT SINGLE-CELL SEQUENCING Researchers at UCSF have developed a method for high throughput single-cell multi-omic sequencing that is rapid, simple to operate, and offers key innovations over existing technologies. Single-cell sequencing technologies refer to the methods to obtain genomics, transcriptomics or multi-omics...

Published: 4/20/2023 | Inventor(s): Adam Abate, Xiangpeng Li, Benjamin Demaree

Keywords(s): Genomic DNA, Hydrogel, Microfluidic, Partitioning, Sequencing, Single-Cell, Transcriptomics

Category(s): Technology Classifications > Biology