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VOLUME IMAGING OF BIOLOGICAL SPECIMENS BY PHOTOCHEMICAL SECTIONING
VOLUME IMAGING OF BIOLOGICAL SPECIMENS BY PHOTOCHEMICAL SECTIONING
Researchers at UC Berkeley and University of Illinois, Chicago have developed a nanoscale volume fluorescence imaging method that enables high-resolution imaging of large tissue volumes.
Hydrogel-based tissue clearing and expansion techniques have improved the ability to study cellular...
Published: 11/6/2024
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Inventor(s): Gokul Upadhyayula, RuiXuan Gao
Keywords(s): Hydrogel, Imaging, Photodegradable
Category(s): Technology Classifications > Biology
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COMPOSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS
COMPOSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS
Researchers at Stanford University have developed a novel therapeutic avenue for the treatment of osteoporosis and other musculoskeletal diseases.
Musculoskeletal disease incidence rates have increased in recent years in response to an aging population. Available...
Published: 9/24/2024
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Inventor(s): Charles Chan, Thomas Ambrosi, Irving Weissman, Michael Longaker, Rahul Sinha, Debashis Sahoo
Keywords(s): Hydrogel, Stem Cell
Category(s): Technology Classifications > Biology
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HYDROGEL PURIFICATION OF CELL MATERIALS FOR PCR-ACTIVATED CELL SORTING
HYDROGEL PURIFICATION OF CELL MATERIALS FOR PCR-ACTIVATED CELL SORTING
Researchers at the NIH and UCSF have developed methods that detect RNA or DNA markers with single molecule sensitivity in cells of interest that allow rapid isolation of these cells or extracts/derivatives of these cells for in-depth transcriptomic, genomic or epigenomic analyses....
Published: 10/26/2023
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Inventor(s): Adam Abate, Iain Clark, Eli Boritz
Keywords(s): High-Throughput, Hydrogel, Microfluidic, Single Cell Genomics, Single Cell Transcriptomics
Category(s): Technology Classifications > Biology
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SINGLE-CELL EPIGENOMIC PROFILING USING DROPLET FLUIDICS AND CHEMICALLY MODIFIED HYDROGELS
SINGLE-CELL EPIGENOMIC PROFILING USING DROPLET FLUIDICS AND CHEMICALLY MODIFIED HYDROGELS
Researchers at UCSF have developed materials and methods for high throughput single cell epigenomic sequencing using a capture/profiling approach with hydrogel scaffolds, thus facilitating a scale and form of epigenomic profiling beyond what has been previously...
Published: 7/6/2023
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Inventor(s): Adam Abate, Xiangpeng Li
Keywords(s): DNA Capture, Droplet, Epigenomic, High-Throughput, Hydrogel, Microfluidic, Single-Cell
Category(s): Technology Classifications > Biology
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PARTITIONING CELLS FOR HIGH-THROUGHPUT SINGLE-CELL SEQUENCING
PARTITIONING CELLS FOR HIGH-THROUGHPUT SINGLE-CELL SEQUENCING
Researchers at UCSF have developed a method for high throughput single-cell multi-omic sequencing that is rapid, simple to operate, and offers key innovations over existing technologies.
Single-cell sequencing technologies refer to the methods to obtain genomics, transcriptomics or multi-omics...
Published: 4/20/2023
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Inventor(s): Adam Abate, Xiangpeng Li, Benjamin Demaree
Keywords(s): Genomic DNA, Hydrogel, Microfluidic, Partitioning, Sequencing, Single-Cell, Transcriptomics
Category(s): Technology Classifications > Biology
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