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HYDROGEL PURIFICATION OF CELL MATERIALS FOR PCR-ACTIVATED CELL SORTING
HYDROGEL PURIFICATION OF CELL MATERIALS FOR PCR-ACTIVATED CELL SORTING
Researchers at the NIH and UCSF have developed methods that detect RNA or DNA markers with single molecule sensitivity in cells of interest that allow rapid isolation of these cells or extracts/derivatives of these cells for in-depth transcriptomic, genomic or epigenomic analyses....
Published: 10/26/2023
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Inventor(s): Adam Abate, Iain Clark, Eli Boritz
Keywords(s): High-Throughput, Hydrogel, Microfluidic, Single Cell Genomics, Single Cell Transcriptomics
Category(s): Technology Classifications > Biology
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METHOD FOR COMBINED GENOME METHYLATION AND VARIATION ANALYSES
METHOD FOR COMBINED GENOME METHYLATION AND VARIATION ANALYSES
Researchers at Stanford have developed improved methods for combined analyses of epigenetics and nucleotide variation in single cells.
Single cell genomic sequencing has allowed characterization of the diversity and evolution of cells within tissues. Recent advances in whole genome...
Published: 3/17/2023
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Inventor(s): Veronica Gonzalez-Pena, Charles Gawad
Keywords(s): Biomolecules, Epigenetics, Methylation, Single Cell, Single Cell Analysis, Single Cell Genomics
Category(s): Technology Classifications > Biology
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SPATIAL GENOMICS WITH SINGLE CELL RESOLUTION
SPATIAL GENOMICS WITH SINGLE CELL RESOLUTION
Researchers at UCSF have developed methods for in situ labelling and sequencing to obtain spatial information and multiomics analysis at a single cell level.
Single-cell sequencing has revealed unappreciated cellular diversity in many ostensibly homogeneous systems and led to an ongoing scientific...
Published: 7/5/2023
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Inventor(s): Cyrille Delley, Adam Abate
Keywords(s): Single Cell, Single Cell Analysis, Single Cell Genomics, Single Cell RNA Sequencing, Single-cell Transcriptomics
Category(s): Technology Classifications > Biology
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QUANTIFICATION OF CELLULAR PROTEINS USING BARCODED BINDING MOIETIES
QUANTIFICATION OF CELLULAR PROTEINS USING BARCODED BINDING MOIETIES
Researchers at Stanford have developed a method enabling quantification of intracellular protein levels using oligonucleotide-barcoded antibodies.
Multiplexing single cell technologies affords researchers the ability to characterize cell states and identify gene regulatory programs...
Published: 3/17/2023
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Inventor(s): William Greenleaf, Amy Chen
Keywords(s): Affinity Reagent, Antibody, Biomolecules, Integrated Screening System, ScRNA-seq, Single Cell, Single Cell Analysis, Single Cell Genomics, Single Cell RNA Sequencing, Single-cell Transcriptomics
Category(s): Technology Classifications > Biology
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MICROFLUIDIC CELL BARCODING AND SEQUENCING
MICROFLUIDIC CELL BARCODING AND SEQUENCING
Researchers at UC Berkeley have developed µCB-seq, a microfluidic cell barcoding and sequencing platform for high-resolution imaging and sequencing of single cells.
Single-cell RNA sequencing (scRNA-seq) enables the investigation of complex biological processes in multicellular organisms with high...
Published: 3/17/2023
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Inventor(s): Aaron Streets, Tyler Chen, Anushka Gupta
Keywords(s): Fluorescence, Genetic Dissection, Microfluidics, ScRNA-seq, Single Cell, Single Cell Analysis, Single Cell Genomics, Single Cell RNA Sequencing, Single-cell Transcriptomics
Category(s): Technology Classifications > Biology
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MULTI-PARAMETRIC AND HIGH-THROUGHPUT SINGLE CELL ANALYSIS
MULTI-PARAMETRIC AND HIGH-THROUGHPUT SINGLE CELL ANALYSIS
Researchers at Stanford, funded in part by the Chan Zuckerberg Biohub, have generated a method for performing multi-parametric and high-throughput single cell genomic and phenotypic analyses.
Single cell -omics, the study of diverse biological processes such as genome, RNA or protein expression...
Published: 3/17/2023
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Inventor(s): Polly Fordyce, Kara Brower, Sandy Klemm, William Greenleaf
Keywords(s): High-Throughput, Microfluidics, Single Cell, Single Cell Analysis, Single Cell Genomics
Category(s): Technology Classifications > Biology
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