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METHODS FOR MEASURING PROTEIN-DNA INTERACTIONS WITH LONG READ DNA SEQUENCING
METHODS FOR MEASURING PROTEIN-DNA INTERACTIONS WITH LONG READ DNA SEQUENCING
Researchers at the University of California Berkeley and Stanford have developed a bespoke, high throughput method for determining DNA-protein interactions in highly repetitive portions of the human genome.
Protein-DNA interactions are essential to the reading, regulation,...
Published: 3/17/2023
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Inventor(s): Aaron Streets, Nicolas Altemose, Annie Maslan
Keywords(s): ChIP-Seq, DNA-Protein Interaction, Epigenetics, Long-read Sequencing
Category(s): Technology Classifications > Biology
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MICROFLUIDIC CELL BARCODING AND SEQUENCING
MICROFLUIDIC CELL BARCODING AND SEQUENCING
Researchers at UC Berkeley have developed µCB-seq, a microfluidic cell barcoding and sequencing platform for high-resolution imaging and sequencing of single cells.
Single-cell RNA sequencing (scRNA-seq) enables the investigation of complex biological processes in multicellular organisms with high...
Published: 3/17/2023
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Inventor(s): Aaron Streets, Tyler Chen, Anushka Gupta
Keywords(s): Fluorescence, Genetic Dissection, Microfluidics, ScRNA-seq, Single Cell, Single Cell Analysis, Single Cell Genomics, Single Cell RNA Sequencing, Single-cell Transcriptomics
Category(s): Technology Classifications > Biology
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IMAGING AND SEQUENCING PROTEIN-DNA INTERACTIONS IN SINGLE CELLS USING INTEGRATED MICROFLUIDICS
IMAGING AND SEQUENCING PROTEIN-DNA INTERACTIONS IN SINGLE CELLS USING INTEGRATED MICROFLUIDICS
Researchers at UC Berkeley have developed an integrated microfluidics method, µDamID (microfluidic DamID), capable of co-determining the cellular location and nucleotide sequence of DNA that is contacted by a protein of interest in a single cell.
Genome...
Published: 3/17/2023
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Inventor(s): Aaron Streets, Nicolas Altemose
Keywords(s): Fluorescence, Genetic Dissection, Microfluidics, Optical Probe, Single Cell, Single Cell Analysis
Category(s): Technology Classifications > Biology
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