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PROBE-BASED DEVICE-FREE SINGLE-CELL RNA PROFILING
PROBE-BASED DEVICE-FREE SINGLE-CELL RNA PROFILING
Researchers at UCSF have developed a novel method for probe-based scRNA-seq.
Single cell RNA sequencing (scRNA-seq) has revolutionized the field of cell biology by enabling nucleic acid profiling at single cell resolution. Typical detection efficiency of scRNA-seq ranges between 5-45%, mostly...
Published: 12/5/2023
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Inventor(s): Bo Huang, Daniel Foyt
Keywords(s): Barcoding, RNA Sequencing, ScRNA-seq
Category(s): Technology Classifications > Biology
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PARTICLE-TEMPLATED EMULSIFICATION IN WELL PLATES
PARTICLE-TEMPLATED EMULSIFICATION IN WELL PLATES
Researchers at UCSF have developed a new method for emulsifying droplet libraries that is highly scalable.
In the past decade, droplet microfluidic technology has revolutionized the sequencing space via single cell RNA-sequencing (scRNA-seq). This technology has vastly increased the resolution of RNA...
Published: 7/6/2023
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Inventor(s): Adam Abate, Daniel Weisgerber
Keywords(s): Digital Droplet PCR, Emulsification, High Throughput Screening, ScRNA-seq
Category(s): Technology Classifications > Biology
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QUANTIFICATION OF CELLULAR PROTEINS USING BARCODED BINDING MOIETIES
QUANTIFICATION OF CELLULAR PROTEINS USING BARCODED BINDING MOIETIES
Researchers at Stanford have developed a method enabling quantification of intracellular protein levels using oligonucleotide-barcoded antibodies.
Multiplexing single cell technologies affords researchers the ability to characterize cell states and identify gene regulatory programs...
Published: 3/17/2023
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Inventor(s): William Greenleaf, Amy Chen
Keywords(s): Affinity Reagent, Antibody, Biomolecules, Integrated Screening System, ScRNA-seq, Single Cell, Single Cell Analysis, Single Cell Genomics, Single Cell RNA Sequencing, Single-cell Transcriptomics
Category(s): Technology Classifications > Biology
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MICROFLUIDIC CELL BARCODING AND SEQUENCING
MICROFLUIDIC CELL BARCODING AND SEQUENCING
Researchers at UC Berkeley have developed µCB-seq, a microfluidic cell barcoding and sequencing platform for high-resolution imaging and sequencing of single cells.
Single-cell RNA sequencing (scRNA-seq) enables the investigation of complex biological processes in multicellular organisms with high...
Published: 3/17/2023
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Inventor(s): Aaron Streets, Tyler Chen, Anushka Gupta
Keywords(s): Fluorescence, Genetic Dissection, Microfluidics, ScRNA-seq, Single Cell, Single Cell Analysis, Single Cell Genomics, Single Cell RNA Sequencing, Single-cell Transcriptomics
Category(s): Technology Classifications > Biology
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MULTI-PARAMETRIC SINGLE CELL ANALYSIS USING SPECTRALLY ENCODED MICROBEADS
MULTI-PARAMETRIC SINGLE CELL ANALYSIS USING SPECTRALLY ENCODED MICROBEADS
Researchers at Stanford and the Chan Zuckerberg Biohub have developed methods for multiple parameter single cell analysis.
Methods to analyze single cells are important for evaluating cell-to-cell variability in biological systems, especially where the characteristics of minority...
Published: 3/17/2023
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Inventor(s): Polly Fordyce, Kara Brower, Alexandera Sockell, Adam White, Yinnian Feng
Keywords(s): Biomolecules, Fluorescence, Microfluidics, RNA-seq, ScRNA-seq, Single Cell, Single Cell Analysis
Category(s): Technology Classifications > Biology
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