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PROBE-BASED DEVICE-FREE SINGLE-CELL RNA PROFILING

PROBE-BASED DEVICE-FREE SINGLE-CELL RNA PROFILING Researchers at UCSF have developed a novel method for probe-based scRNA-seq. Single cell RNA sequencing (scRNA-seq) has revolutionized the field of cell biology by enabling nucleic acid profiling at single cell resolution. Typical detection efficiency of scRNA-seq ranges between 5-45%, mostly...

Published: 12/5/2023 | Inventor(s): Bo Huang, Daniel Foyt

Keywords(s): Barcoding, RNA Sequencing, ScRNA-seq

Category(s): Technology Classifications > Biology

RECONSTITUTION OF SPLIT-HALOTAG VIA ORTHOGONAL TAG BINDING DOMAINS

RECONSTITUTION OF SPLIT-HALOTAG VIA ORTHOGONAL TAG BINDING DOMAINS Researchers at UCSF have developed a method using split HaloTags to tag multiple proteins in a single assay and measure their interactions. Due to new technologies such as CRISPR/Cas9 gene editing, it is now easier to modify DNA than at any other point in human history. One of the...

Published: 5/18/2023 | Inventor(s): David Brown, Suraj Makhija, Bo Huang

Keywords(s): FACS, HaloTag, Knock-In Cell Lines, Protein Fragment, Self-Complementing Protein Fragments, Split Protein System

Category(s): Technology Classifications > Biology