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DELIVERY OF CRISPR COMPONENTS
Researchers at UC Berkeley have developed novel strategies for the delivery of CRISPR gene editing components.
While CRISPR-based gene editing holds great promise for treating genetic diseases, it often involves DNA breaks or base changes that can cause off-target effects, cell damage, or unpredictable outcomes. Additionally, these changes are often...
Published: 10/23/2025
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Inventor(s): James Nunez, Da Xu, Swen Besselink
Keywords(s): CRISPR, Epigenetics
Category(s): Technology Classifications > Biology
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METHODS FOR MEASURING PROTEIN-DNA INTERACTIONS WITH LONG READ DNA SEQUENCING
METHODS FOR MEASURING PROTEIN-DNA INTERACTIONS WITH LONG READ DNA SEQUENCING
Researchers at the University of California Berkeley and Stanford have developed a bespoke, high throughput method for determining DNA-protein interactions in highly repetitive portions of the human genome.
Protein-DNA interactions are essential to the reading, regulation,...
Published: 1/31/2025
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Inventor(s): Aaron Streets, Nicolas Altemose, Annie Maslan
Keywords(s): ChIP-Seq, DNA-Protein Interaction, Epigenetics, Long-read Sequencing
Category(s): Technology Classifications > Biology
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METHOD FOR COMBINED GENOME METHYLATION AND VARIATION ANALYSES
METHOD FOR COMBINED GENOME METHYLATION AND VARIATION ANALYSES
Researchers at Stanford have developed improved methods for combined analyses of epigenetics and nucleotide variation in single cells.
Single cell genomic sequencing has allowed characterization of the diversity and evolution of cells within tissues. Recent advances in whole genome...
Published: 12/5/2024
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Inventor(s): Veronica Gonzalez-Pena, Charles Gawad
Keywords(s): Biomolecules, Epigenetics, Methylation, Single Cell, Single Cell Analysis, Single Cell Genomics
Category(s): Technology Classifications > Biology
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