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DESIGN OF UNIVERSAL H5 INFLUENZA VIRUS VACCINE CANDIDATES VIA ANTIGEN REORIENTATION
DESIGN OF UNIVERSAL H5 INFLUENZA VIRUS VACCINE CANDIDATES VIA ANTIGEN REORIENTATION
Researchers at Stanford University have developed novel universal vaccine candidates for H5 influenza viruses.
Influenza remains a serious threat to public health. H5 avian influenza strains are among the most concerning despite lack of documented human to human...
Published: 9/24/2024
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Inventor(s): Duo Xu, Peter Kim
Keywords(s): Immunofocusing, Vaccine
Category(s): Technology Classifications > Biology
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HIGH THROUGHPUT METHOD FOR SCREENING LIPID NANOPARTICLE EFFICACY AND CYTOTOXICITY
HIGH THROUGHPUT METHOD FOR SCREENING LIPID NANOPARTICLE EFFICACY AND CYTOTOXICITY
Researchers at Berkeley have developed synthetic cell membranes that are optimized for screening the toxicity and efficacy of lipid nanoparticle formulations in vitro, in a high throughput format.
Lipid nanoparticles (LNPs) represent a highly effective and efficient...
Published: 4/22/2024
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Inventor(s): Markita Landry, Alison Lui
Keywords(s): Nanoparticle, SARS-CoV-2, Vaccine
Category(s): Technology Classifications > Biology
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DESIGN OF A UNIVERSAL INFLUENZA VACCINE CANDIDATES VIA ANTIGEN REORIENTATION
DESIGN OF A UNIVERSAL INFLUENZA VACCINE CANDIDATES VIA ANTIGEN REORIENTATION
Researchers at Stanford have developed a novel universal influenza vaccine candidate.
Vaccines are a major feat of biomedical innovation. Successful vaccines produce broad humoral immunity to a pathogen to prevent subsequent infection. In this vein, adjuvants are compounds...
Published: 12/5/2023
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Inventor(s): Duo Xu, Peter Kim
Keywords(s): Adjuvant, Alum, Infectious Disease, Vaccine
Category(s): Technology Classifications > Biology
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IMMUNOGENIC EBOLAVIRUS FUSION PROTEINS AND RELATED METHODS
IMMUNOGENIC EBOLAVIRUS FUSION PROTEINS AND RELATED METHODS
Researchers at Stanford have developed a novel vaccine strategy for ebolavirus using fusion proteins composed of the virus’ glycoprotein.
Hemorrhagic fevers have become a major public health issue in Africa, the most notable of which being Ebola. Ebola has a notably high mortality...
Published: 10/6/2023
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Inventor(s): Peter Kim, Duo Xu, Abigail Powell
Keywords(s): Ebola Virus, Infectious Disease, Vaccine
Category(s): Technology Classifications > Biology
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IMMUNOGENIC CORONAVIRUS FUSION PROTEINS AND RELATED METHODS
IMMUNOGENIC CORONAVIRUS FUSION PROTEINS AND RELATED METHODS
Researchers at Stanford have developed fusion proteins as a novel vaccine strategy for SARS-CoV2.
As the causative force of the COVID-19 pandemic, SARS-CoV2 caused massive sustained morbidity, mortality, and societal disruption worldwide. Though COVID-19 has largely transitioned from...
Published: 12/3/2024
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Inventor(s): Peter Kim, Natalia Friedland, Mrinmoy Sanyal, Payton Weidenbacher
Keywords(s): Coronavirus, COVID, COVID-19, Infectious Disease, Vaccine
Category(s): Technology Classifications > Biology
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CHEMICALLY MODIFIED BACTERIAL PEPTIDOGLYCAN COMPOSITIONS AND USES THEREOF
CHEMICALLY MODIFIED BACTERIAL PEPTIDOGLYCAN COMPOSITIONS AND USES THEREOF
Researchers at Stanford have developed a new microparticle vaccine scaffold for the development of immunogenic subunit vaccines.
Vaccines are one of the most important biomedical advances of the 20th century. Protein vaccines, often referred to as subunit vaccines, have proved...
Published: 8/17/2023
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Inventor(s): Peter Kim, Carolyn Bertozzi, Frances RodrÃguez-Rivera
Keywords(s): Adjuvant, Bacteria, Peptidoglycan, Vaccine
Category(s): Technology Classifications > Biology
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MEASUREMENT OF AFUCOSYLATED IgG Fc GLYCANS TO PREDICT RISK OF SEVERE COVID-19 DISEASE
MEASUREMENT OF AFUCOSYLATED IgG Fc GLYCANS TO PREDICT RISK OF SEVERE COVID-19 DISEASE
Researchers at Stanford have developed a method for identifying a subject that is at risk of progression to clinically significant COVID-19 infection or disease.
A minority of individuals infected with SARS-CoV-2 mount an extreme inflammatory response that...
Published: 3/17/2023
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Inventor(s): Taia Wang
Keywords(s): Afucosylation, Antibody, COVID-19, Glycoform, Glycosylation, IgG, Non-Neutralizing, Receptor, Symptom, Vaccine
Category(s): Technology Classifications > Biology
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BROADLY NEUTRALIZING ANTIBODIES AGAINST DENGUE VIRUS
BROADLY NEUTRALIZING ANTIBODIES AGAINST DENGUE VIRUS
Researchers at Stanford and the Chan Zuckerberg Biohub have discovered cross reactive, broadly neutralizing human antibodies against all serotypes of dengue virus.
Dengue virus (DENV) is transmitted to humans through mosquitos and causes approximately 400 million global infections each year. DENV...
Published: 3/17/2023
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Inventor(s): Fabio Zanini, Derek Croote, Makeda Robinson, Leslie Goo, Stephen Quake, Shirit Einav, Krista McCutcheon
Keywords(s): Broadly Neutralizing Antibodies (bNAbs), Dengue, Flavivirus, Monoclonal Antibodies (mAbs), Single-cell Transcriptomics, Vaccine
Category(s): Technology Classifications > Biology
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A STRATEGY FOR CREATING VACCINES TO ELICIT ANTIBODIES TARGETING A SPECIFIC EPITOPE
A STRATEGY FOR CREATING VACCINES TO ELICIT ANTIBODIES TARGETING A SPECIFIC EPITOPE
Researchers at Stanford, funded in part by the Chan Zuckerberg Biohub, have developed PMD (Protect, Modify, Deprotect), an immunofocusing strategy that can be used in vaccine development for the generation of antibodies targeting a specific epitope.
Vaccine development...
Published: 3/17/2023
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Inventor(s): Payton Weidenbacher, Peter Kim
Keywords(s): Antibody, Epitope Shield, Immunofocusing, mAb, Monoclonal Antibody, Vaccine
Category(s): Technology Classifications > Biology
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