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MEASUREMENT OF AFUCOSYLATED IgG Fc GLYCANS TO PREDICT RISK OF SEVERE COVID-19 DISEASE
MEASUREMENT OF AFUCOSYLATED IgG Fc GLYCANS TO PREDICT RISK OF SEVERE COVID-19 DISEASE
Researchers at Stanford have developed a method for identifying a subject that is at risk of progression to clinically significant COVID-19 infection or disease.
A minority of individuals infected with SARS-CoV-2 mount an extreme inflammatory response that...
Published: 3/17/2023
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Inventor(s): Taia Wang
Keywords(s): Afucosylation, Antibody, COVID-19, Glycoform, Glycosylation, IgG, Non-Neutralizing, Receptor, Symptom, Vaccine
Category(s): Technology Classifications > Biology
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AUTOANTIBODIES AS BIOMARKERS FOR LIPODYSTROPHY
AUTOANTIBODIES AS BIOMARKERS FOR LIPODYSTROPHY
Researchers at UCSF and the Chan Zuckerberg Biohub have developed methods to identify a subject that is at risk of developing autoimmune-related lipodystrophy.
Lipodystrophy is a clinical phenotype defined by a reduction in subcutaneous fat or adipose tissue. Excessive fat loss can lead to an imbalance...
Published: 3/17/2023
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Inventor(s): Caleigh Mandel-Brehm, Joseph DeRisi, Mark Anderson
Keywords(s): Antibody, Autoantibody, Autoimmune, Biomolecules, Diagnosis, IgG, Immunotherapy, Lipodystrophy
Category(s): Technology Classifications > Biology
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BIOSENSOR DETECTION ASSAY FOR ANTI-SARS-COV-2 ANTIBODIES
BIOSENSOR DETECTION ASSAY FOR ANTI-SARS-COV-2 ANTIBODIES
Researchers at UCSF and the Chan Zuckerberg Biohub have developed a serological detection assay for anti-SARS-CoV-2 antibodies.
COVID-19, caused by the SARS-CoV-2 virus, has spread throughout the world. Early detection of disease using viral detection assays is critical for containing the spread...
Published: 3/17/2023
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Inventor(s): James Wells, Susanna Elledge, Xin Zhou
Keywords(s): Antibody, Biosensor System, Diagnosis, Epitope Shield, IgG
Category(s): Technology Classifications > Biology
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AFUCOSYLATED MATERNAL ANTI-DENGUE IGGS ARE A BIOMARKER FOR SUSCEPTIBILITY TO SEVERE DENGUE DISEASE IN INFANTS
AFUCOSYLATED MATERNAL ANTI-DENGUE IGGS ARE A BIOMARKER FOR SUSCEPTIBILITY TO SEVERE DENGUE DISEASE IN INFANTS
Researchers at Stanford, funded in part by the Chan Zuckerberg Biohub, have developed a method for determining infant susceptibility to severe dengue disease through measurement of maternal anti-dengue IgG.
Mortality rates in severe dengue...
Published: 3/17/2023
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Inventor(s): Taia Wang
Keywords(s): Afucosylation, Antibody, Dengue, Fc Domain, Glycosylation, IgG
Category(s): Technology Classifications > Biology
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