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COMPOSITIONS AND METHODS RELATED TO TRANSCOBALAMIN RECEPTOR AUTOANTIBODIES
COMPOSITIONS AND METHODS RELATED TO TRANSCOBALAMIN RECEPTOR AUTOANTIBODIES
Researchers at CZ Biohub SF and UCSF have developed methods and kits to detect autoantibodies targeting the transcobalamin receptor CD320, which is associated with neurological symptoms in certain patients, as well as methods to treat patients with this condition.
Vitamin...
Published: 10/26/2023
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Inventor(s): John Pluvinage, Michael Wilson, Joseph DeRisi, Samuel Pleasure
Keywords(s): Autoantibody, Brain, Vitamin B12
Category(s): Technology Classifications > Biology
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AUTOANTIBODIES AS BIOMARKERS FOR LIPODYSTROPHY
AUTOANTIBODIES AS BIOMARKERS FOR LIPODYSTROPHY
Researchers at UCSF and the Chan Zuckerberg Biohub have developed methods to identify a subject that is at risk of developing autoimmune-related lipodystrophy.
Lipodystrophy is a clinical phenotype defined by a reduction in subcutaneous fat or adipose tissue. Excessive fat loss can lead to an imbalance...
Published: 3/17/2023
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Inventor(s): Caleigh Mandel-Brehm, Joseph DeRisi, Mark Anderson
Keywords(s): Antibody, Autoantibody, Autoimmune, Biomolecules, Diagnosis, IgG, Immunotherapy, Lipodystrophy
Category(s): Technology Classifications > Biology
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AUTOANTIBODIES AS BIOMARKERS FOR AUTOIMMUNE POLYGLANDULAR SYNDROME TYPE 1
AUTOANTIBODIES AS BIOMARKERS FOR AUTOIMMUNE POLYGLANDULAR SYNDROME TYPE 1
Researchers at UCSF and the Chan Zuckerberg Biohub have identified multiple common autoantibody targets in APS1 patients through proteome-wide programmable phage-display.
The identification of autoantigens remains a critical challenge for understanding and treating autoimmune...
Published: 3/17/2023
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Inventor(s): Sara Vazquez, Mark Anderson, Joseph DeRisi
Keywords(s): Antibody, Autoantibody, Diagnosis, Particle Display, Serum
Category(s): Technology Classifications > Biology
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AUTOANTIBODIES AS BIOMARKER OF PARANEOPLASTIC ENCEPHALITIS ASSOCIATED WITH TESTICULAR CANCER
AUTOANTIBODIES AS BIOMARKER OF PARANEOPLASTIC ENCEPHALITIS ASSOCIATED WITH TESTICULAR CANCER
Researchers at the Chan Zuckerberg Biohub, UCSF and the Mayo Clinic have discovered a novel biomarker for an autoimmune disease that affects patients with testicular cancer. The disease, known as “testicular cancer-associated paraneoplastic encephalitis,”...
Published: 3/17/2023
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Inventor(s): Joseph DeRisi, Michael Wilson, Caleigh Mandel-Brehm, Brian O'Donovan, Sean Pittock, Divyanshu Dubey, Thomas Kryzer, Vanda Lennon, Andrew McKeon
Keywords(s): Antibody, Autoantibody, Diagnosis, KLHL11, Neurology, Testicular Cancer
Category(s): Technology Classifications > Biology
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