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­GENERATION OF ANTIGEN-SPECIFIC T AND B CELLS USING ENGINEERED COMMENSALS
­GENERATION OF ANTIGEN-SPECIFIC T AND B CELLS USING ENGINEERED COMMENSALS Researchers at Stanford have developed methods to link antigenic or immunomodulatory molecules to bacterial surface proteins of commensal bacteria that result in a high immune response when applied to an epithelial surface of a mammal. Commensal microbiota reside primarily...
Published: 2/14/2024   |   Inventor(s): Michael Fischbach, Djenet Bousbaine, Christopher Barnes, Katherine Bauman, Yasmine Belkaid
Keywords(s): Antigen, Bacteria, Immunomodulator
Category(s): Technology Classifications > Biology
BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
­BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS Researchers at Stanford have developed a new avenue for stimulating T effector and Treg immune cells in an antigen-specific manner. Commensal microbiota have been shown to functionally regulate the innate and adaptive immune systems and must establish distinct niches at barrier sites throughout...
Published: 10/6/2023   |   Inventor(s): Michael Fischbach, Kazuki Nagashima, Yiyin Chen, Djenet Bousbaine
Keywords(s): Autoimmune, Bacteria, T-Cell Activation
Category(s): Technology Classifications > Biology
­BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
­BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS Researchers at Stanford have developed a new avenue for stimulating T effector and Treg immune cells in an antigen-specific manner. Commensal microbiota have been shown to functionally regulate the innate and adaptive immune systems and must establish distinct niches at barrier sites throughout...
Published: 10/6/2023   |   Inventor(s): Michael Fischbach, Kazuki Nagashima, Yiyin Chen
Keywords(s): Autoimmune, Bacteria, T-Cell Activation
Category(s): Technology Classifications > Biology
CHEMICALLY MODIFIED BACTERIAL PEPTIDOGLYCAN COMPOSITIONS AND USES THEREOF
CHEMICALLY MODIFIED BACTERIAL PEPTIDOGLYCAN COMPOSITIONS AND USES THEREOF Researchers at Stanford have developed a new microparticle vaccine scaffold for the development of immunogenic subunit vaccines. Vaccines are one of the most important biomedical advances of the 20th century. Protein vaccines, often referred to as subunit vaccines, have proved...
Published: 8/17/2023   |   Inventor(s): Peter Kim, Carolyn Bertozzi, Frances RodrÃguez-Rivera
Keywords(s): Adjuvant, Bacteria, Peptidoglycan, Vaccine
Category(s): Technology Classifications > Biology