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BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
Researchers at Stanford have developed a new avenue for stimulating T effector and Treg immune cells in an antigen-specific manner.
Commensal microbiota have been shown to functionally regulate the innate and adaptive immune systems and must establish distinct niches at barrier sites throughout...
Published: 10/6/2023
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Inventor(s): Michael Fischbach, Kazuki Nagashima, Yiyin Chen, Djenet Bousbaine
Keywords(s): Autoimmune, Bacteria, T-Cell Activation
Category(s): Technology Classifications > Biology
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BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
Researchers at Stanford have developed a new avenue for stimulating T effector and Treg immune cells in an antigen-specific manner.
Commensal microbiota have been shown to functionally regulate the innate and adaptive immune systems and must establish distinct niches at barrier sites throughout...
Published: 10/6/2023
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Inventor(s): Michael Fischbach, Kazuki Nagashima, Yiyin Chen
Keywords(s): Autoimmune, Bacteria, T-Cell Activation
Category(s): Technology Classifications > Biology
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HIGH-THROUGHPUT FORCE-DEPENDENT CELLULAR RESPONSE ASSAY USING SPECTRALLY ENCODED SMART BEADS
HIGH-THROUGHPUT FORCE-DEPENDENT CELLULAR RESPONSE ASSAY USING SPECTRALLY ENCODED SMART BEADS
Researchers at Stanford have developed a technology that uses biomechanical force to initiate T-cell triggering in a high throughput method, facilitating the exploration of the force- and sequence-dependent landscape of T-cell responses.
Adaptive immunity...
Published: 3/17/2023
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Inventor(s): Xiang Zhao, Adam White, Polly Fordyce, Yinnian Feng, K Garcia
Keywords(s): Catch Bond, High-Throughput Mechanobiology, Ligand Discrimination, Mechanotransduction, Single-Cell Microfluidics, Spectrally Encoded Beads, T-Cell Activation, T-Cell Biophysics, T-Cell Receptor
Category(s): Technology Classifications > Biology
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