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GERMLINE AND CANCER SUBTYPES FOR MONITORING AND TREATMENT
GERMLINE AND CANCER SUBTYPES FOR MONITORING AND TREATMENT
Researchers at Stanford have developed practical applications that use germline information (e.g., germline epitope burden) for diagnosis, monitoring and treatment of cancer.
Cancer represents a wide spectrum of molecularly and morphologically diverse diseases. Individuals with the same...
Published: 10/26/2023
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Inventor(s): Christina Curtis, Kathleen Houlahan
Keywords(s): Cancer, Immunotherapy
Category(s): Technology Classifications > Biology
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COMPOSITIONS AND METHODS FOR INHIBITING FSP1
COMPOSITIONS AND METHODS FOR INHIBITING FSP1
Researchers at UC Berkeley have developed ferroptosis suppressor protein 1 (FSP1) inhibitors and methods for their use in cancer therapy.
Ferroptosis is an iron-dependent, non-apoptotic form of regulated cell death that is characterized by the accumulation of oxidatively damaged phospholipids. Ferroptosis...
Published: 9/14/2023
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Inventor(s): James Olzmann, Kirill Bersuker, Julia Schaletzky, Edward Wehri
Keywords(s): Cancer, Ferroptosis, FSP1
Category(s): Technology Classifications > Chemistry
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METHODS, COMPOSITIONS AND SYSTEMS FOR PROFILING OR PREDICTING IMMUNE RESPONSE
METHODS, COMPOSITIONS AND SYSTEMS FOR PROFILING OR PREDICTING IMMUNE RESPONSE
Researchers at Avail Bio, Inc., UCSF and the Chan Zuckerberg Biohub have developed a proteomic technology for capturing the immune response against non-wild type antigens.
Immuno-oncologic research demonstrating tumor recognition by the immune system has led to the development...
Published: 6/1/2023
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Inventor(s): Nima Emami, Clinton Cario, Joseph DeRisi, John Witte
Keywords(s): Antibody, Cancer, Immunotherapy, Oncology, Particle Display
Category(s): Technology Classifications > Biology
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COMPOSITIONS AND METHODS FOR MODULATING LEFTY AND BMP PROTEINS
COMPOSITIONS AND METHODS FOR MODULATING LEFTY AND BMP PROTEINS
Researchers at Stanford, funded in part by the Chan Zuckerberg Biohub, have surprisingly found that LEFTY1 suppresses not only the SMAD2/3 signaling pathway (a pathway activated by Nodal signaling) but also the SMAD1/5/8 signaling pathway (a pathway activated by BMP proteins, including...
Published: 3/17/2023
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Inventor(s): Michael Clarke, Neethan Lobo, Maider Ugalde
Keywords(s): BMP, Breast Cancer, Cancer, LEFTY, Neoplasm, TGF-β Superfamily
Category(s): Technology Classifications > Biology
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METHODS FOR TREATING TRIPLE NEGATIVE BREAST CANCER
METHODS FOR TREATING TRIPLE NEGATIVE BREAST CANCER
Researchers at Stanford, funded in part by the Chan Zuckerberg Biohub, have developed a method for treating and predicting treatment efficacy of triple negative breast cancer (TNBC).
TNBC is an aggressive subtype of breast cancer that is characterized by a lack of expression of three receptors commonly...
Published: 3/17/2023
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Inventor(s): Michael Clarke, Robert Hsieh
Keywords(s): Breast Cancer, Cancer, CDK19, Oncology, TNBC, Triple Negative Breast Cancer
Category(s): Technology Classifications > Biology
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