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GENERATION OF ANTIGEN-SPECIFIC T AND B CELLS USING ENGINEERED COMMENSALS
GENERATION OF ANTIGEN-SPECIFIC T AND B CELLS USING ENGINEERED COMMENSALS
Researchers at Stanford have developed methods to link antigenic or immunomodulatory molecules to bacterial surface proteins of commensal bacteria that result in a high immune response when applied to an epithelial surface of a mammal.
Commensal microbiota reside primarily...
Published: 2/14/2024
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Inventor(s): Michael Fischbach, Djenet Bousbaine, Christopher Barnes, Katherine Bauman, Yasmine Belkaid
Keywords(s): Antigen, Bacteria, Immunomodulator
Category(s): Technology Classifications > Biology
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BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
Researchers at Stanford have developed a new avenue for stimulating T effector and Treg immune cells in an antigen-specific manner.
Commensal microbiota have been shown to functionally regulate the innate and adaptive immune systems and must establish distinct niches at barrier sites throughout...
Published: 10/6/2023
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Inventor(s): Michael Fischbach, Kazuki Nagashima, Yiyin Chen, Djenet Bousbaine
Keywords(s): Autoimmune, Bacteria, T-Cell Activation
Category(s): Technology Classifications > Biology
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BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
BACTERIA-ENGINEERED TO ELICIT ANTIGEN-SPECIFIC T-CELLS
Researchers at Stanford have developed a new avenue for stimulating T effector and Treg immune cells in an antigen-specific manner.
Commensal microbiota have been shown to functionally regulate the innate and adaptive immune systems and must establish distinct niches at barrier sites throughout...
Published: 10/6/2023
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Inventor(s): Michael Fischbach, Kazuki Nagashima, Yiyin Chen
Keywords(s): Autoimmune, Bacteria, T-Cell Activation
Category(s): Technology Classifications > Biology
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HIGH-CAPACITY LENTIVIRAL VECTORS
HIGH-CAPACITY LENTIVIRAL VECTORS
Researchers at Stanford have developed new lentiviral vectors that are able to deliver more genetic information than currently available vectors, aiding in the development of gene therapy.
Gene therapy is one of the most promising therapeutic avenues in translational medicine. This method involves the genetic engineering...
Published: 8/17/2023
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Inventor(s): Michael Fischbach, Brian Caliando, Gabriel Filsinger
Keywords(s): Gene Therapy, Lentiviral Vector
Category(s): Technology Classifications > Biology
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