METHOD FOR MASSIVELY PARALLEL SCREENING OF APTAMER SWITCHES
METHOD FOR MASSIVELY PARALLEL SCREENING OF APTAMER SWITCHES
Researchers at Stanford have developed a massively parallel screening strategy to screen for target-responsive molecular switches.
Target-responsive RNA- and DNA-based molecular switches have potential utility in a variety of technological applications. Such biosensors are typically...
Published: 3/17/2023
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Inventor(s): Hyongsok Soh
Keywords(s): Affinity Reagent, Aptamer, Base-Modified Nucleotide, Biomolecules, Biosensor System, Fluorescence, High-Throughput, Integrated Screening System, Molecular Switches, Non-Natural Nucleotide
Category(s): Technology Classifications > Biology
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INDEPENDENT CONTROL OF THE THERMODYNAMIC AND KINETIC PROPERTIES OF APTAMER SWITCHES
INDEPENDENT CONTROL OF THE THERMODYNAMIC AND KINETIC PROPERTIES OF APTAMER SWITCHES
Researchers at Stanford and the Chan Zuckerberg Biohub have developed methods for independent tuning of aptamer switching binding affinities and kinetics.
Aptamers are useful molecular switches with excellent binding properties that can reversibly change their confirmation...
Published: 3/17/2023
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Inventor(s): Hyongsok Soh, Brandon Wilson, Amani Hariri
Keywords(s): Affinity Reagent, Aptamer, Biosensor System, Molecular Switches
Category(s): Technology Classifications > Biology
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PROGRAMMABLE ANTIBODY-BASED MOLECULAR SWITCHES FOR TARGET ANALYTE DETECTION
PROGRAMMABLE ANTIBODY-BASED MOLECULAR SWITCHES FOR TARGET ANALYTE DETECTION
Researchers at Stanford and the Chan Zuckerberg Biohub have developed antibody-based molecular switches for target analyte detection.
The development of technologies that can monitor circulating biomolecules have transformed modern medicine. Molecular switches, which change...
Published: 3/17/2023
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Inventor(s): Jing Pan, Ian Paul Thompson, Brandon Wilson, Hyongsok Soh
Keywords(s): Affinity Reagent, Antibody, Biosensor System, Fc Domain, Molecular Switches
Category(s): Technology Classifications > Biology
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REAL-TIME OPTICAL BIOSENSORS FOR IN VIVO DETECTION
REAL-TIME OPTICAL BIOSENSORS FOR IN VIVO DETECTION
Researchers at Stanford and the Chan Zuckerberg Biohub have developed a platform for real-time and continuous detection of biomolecules in vivo.
The development of technologies that can monitor circulating biomolecules in vivo, such as continuous glucose monitors, have transformed modern medicine....
Published: 3/17/2023
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Inventor(s): Amani Hariri, Constantin Dory, Alyssa Cartwright, Jelena Vuckovic, Hyongsok Soh
Keywords(s): Aptamer, Biomolecules, Biosensor System, Fluorescence, Molecular Switches, Optical Probe
Category(s): Technology Classifications > Biology, Technology Classifications > Engineering
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