Search Results - non-natural+nucleotide

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METHOD FOR MASSIVELY PARALLEL SCREENING OF APTAMER SWITCHES

METHOD FOR MASSIVELY PARALLEL SCREENING OF APTAMER SWITCHES Researchers at Stanford have developed a massively parallel screening strategy to screen for target-responsive molecular switches. Target-responsive RNA- and DNA-based molecular switches have potential utility in a variety of technological applications. Such biosensors are typically...

Published: 3/17/2023 | Inventor(s): Hyongsok Soh

Keywords(s): Affinity Reagent, Aptamer, Base-Modified Nucleotide, Biomolecules, Biosensor System, Fluorescence, High-Throughput, Integrated Screening System, Molecular Switches, Non-Natural Nucleotide

Category(s): Technology Classifications > Biology

COMPOSITIONS AND METHODS INVOLVING NON-NATURAL APTAMER LIBRARIES

COMPOSITIONS AND METHODS INVOLVING NON-NATURAL APTAMER LIBRARIES Researchers at Stanford, funded in part by the Chan Zuckerberg Biohub, have developed Click-PD, a framework for the customizable generation of non-natural, base-modified aptamer libraries with diverse chemical modifications. These libraries are used in a high-throughput particle display...

Published: 3/17/2023 | Inventor(s): Jia Niu, Chelsea Gordon, Hyongsok Soh

Keywords(s): Aptamer, ConA, Non-Natural Nucleotide, Particle Display

Category(s): Technology Classifications > Biology, Technology Classifications > Chemistry