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INDEPENDENT CONTROL OF THE THERMODYNAMIC AND KINETIC PROPERTIES OF APTAMER SWITCHES

INDEPENDENT CONTROL OF THE THERMODYNAMIC AND KINETIC PROPERTIES OF APTAMER SWITCHES Researchers at Stanford and the Chan Zuckerberg Biohub have developed methods for independent tuning of aptamer switching binding affinities and kinetics. Aptamers are useful molecular switches with excellent binding properties that can reversibly change their confirmation...

Published: 3/17/2023 | Inventor(s): Hyongsok Soh, Brandon Wilson, Amani Hariri

Keywords(s): Affinity Reagent, Aptamer, Biosensor System, Molecular Switches

Category(s): Technology Classifications > Biology

PROGRAMMABLE ANTIBODY-BASED MOLECULAR SWITCHES FOR TARGET ANALYTE DETECTION

PROGRAMMABLE ANTIBODY-BASED MOLECULAR SWITCHES FOR TARGET ANALYTE DETECTION Researchers at Stanford and the Chan Zuckerberg Biohub have developed antibody-based molecular switches for target analyte detection. The development of technologies that can monitor circulating biomolecules have transformed modern medicine. Molecular switches, which change...

Published: 3/17/2023 | Inventor(s): Jing Pan, Ian Paul Thompson, Brandon Wilson, Hyongsok Soh

Keywords(s): Affinity Reagent, Antibody, Biosensor System, Fc Domain, Molecular Switches

Category(s): Technology Classifications > Biology