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INDEPENDENT CONTROL OF THE THERMODYNAMIC AND KINETIC PROPERTIES OF APTAMER SWITCHES

INDEPENDENT CONTROL OF THE THERMODYNAMIC AND KINETIC PROPERTIES OF APTAMER SWITCHES Researchers at Stanford and the Chan Zuckerberg Biohub have developed methods for independent tuning of aptamer switching binding affinities and kinetics. Aptamers are useful molecular switches with excellent binding properties that can reversibly change their confirmation...

Published: 3/17/2023 | Inventor(s): Hyongsok Soh, Brandon Wilson, Amani Hariri

Keywords(s): Affinity Reagent, Aptamer, Biosensor System, Molecular Switches

Category(s): Technology Classifications > Biology

REAL-TIME OPTICAL BIOSENSORS FOR IN VIVO DETECTION

REAL-TIME OPTICAL BIOSENSORS FOR IN VIVO DETECTION Researchers at Stanford and the Chan Zuckerberg Biohub have developed a platform for real-time and continuous detection of biomolecules in vivo. The development of technologies that can monitor circulating biomolecules in vivo, such as continuous glucose monitors, have transformed modern medicine....

Published: 3/17/2023 | Inventor(s): Amani Hariri, Constantin Dory, Alyssa Cartwright, Jelena Vuckovic, Hyongsok Soh

Keywords(s): Aptamer, Biomolecules, Biosensor System, Fluorescence, Molecular Switches, Optical Probe

Category(s): Technology Classifications > Biology, Technology Classifications > Engineering