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PHAGE-MEDIATED DELIVERY OF GENES TO GUT MICROBIOME
PHAGE-MEDIATED DELIVERY OF GENES TO GUT MICROBIOME
Researchers at UCSF have developed methods to engineer bacteriophage for gene delivery to gut microbiome.
There is broad interest in the influence that the gut microbiome has on host health and disease. Mechanistic insights into the role of the human gut microbiome in the predisposition to and...
Published: 3/17/2023
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Inventor(s): Kathy Lam, Peter Spanogiannopoulos, Peter Turnbaugh
Keywords(s): Bacterial Pathogenesis, CRISPR, Genome Editing
Category(s): Technology Classifications > Biology
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BARCODED CLONAL TRACKING OF GENE TARGETING IN CELLS
BARCODED CLONAL TRACKING OF GENE TARGETING IN CELLS
Researchers at Stanford and the Chan Zuckerberg Biohub have developed a methodology to monitor cell expansion and differentiation following targeted genomic modification.
Targeted DNA correction of disease-causing mutations offers promise in the treatment of genetic diseases. Following targeted...
Published: 3/17/2023
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Inventor(s): Daniel Dever, Rajiv Sharma, Matthew Porteus, Ravindra Majeti, Joab Camarena, Thomas Koehnke
Keywords(s): Blood, Cas9, CRISPR, Genome Editing, Genome Integration, Nuclease
Category(s): Technology Classifications > Biology
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DISCOVERY OF A HIGHLY THERMOSTABLE CAS9 VARIANT
DISCOVERY OF A HIGHLY THERMOSTABLE CAS9 VARIANT
Researchers at Stanford and the Chan Zuckerberg Biohub have discovered a Cas9 protein variant from Ignavibacterium that is thermostable at elevated temperatures.
The application of genome editing technologies, such as clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated...
Published: 3/17/2023
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Inventor(s): Stephen Quake, Stephanie Schmidt, Feiqiao Yu, Paul Blainey, Andrew May
Keywords(s): Cas9, CRISPR, Genome Editing, Nuclease, Themostable
Category(s): Technology Classifications > Biology
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