Search Results - bacterial+pathogenesis

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PHAGE-MEDIATED DELIVERY OF GENES TO GUT MICROBIOME

PHAGE-MEDIATED DELIVERY OF GENES TO GUT MICROBIOME Researchers at UCSF have developed methods to engineer bacteriophage for gene delivery to gut microbiome. There is broad interest in the influence that the gut microbiome has on host health and disease. Mechanistic insights into the role of the human gut microbiome in the predisposition to and...

Published: 3/17/2023 | Inventor(s): Kathy Lam, Peter Spanogiannopoulos, Peter Turnbaugh

Keywords(s): Bacterial Pathogenesis, CRISPR, Genome Editing

Category(s): Technology Classifications > Biology

ENABLING GENETIC ANALYSIS OF DIVERSE BACTERIA WITH MOBILE-CRISPRi

ENABLING GENETIC ANALYSIS OF DIVERSE BACTERIA WITH MOBILE-CRISPRi Researchers at UCSF, funded in part by the Chan Zuckerberg Biohub, have generated a modular and effective CRISPRi system for the genetic dissection of non-model bacteria. The vast majority of bacteria, including human pathogens and microbiome species, lack genetic tools needed to associate...

Published: 3/17/2023 | Inventor(s): Jason Peters, Carol Gross, Oren Rosenberg

Keywords(s): Bacterial Pathogenesis, CRISPRi, Genetic Dissection, Genome Integration, Non-Model Bacteria

Category(s): Technology Classifications > Biology