Search Results - crispri

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ENGINEERED MULTI-SEGMENTED RNA VIRUSES FOR LARGE-SCALE COMBINATORIAL GENETIC SCREENING
­ENGINEERED MULTI-SEGMENTED RNA VIRUSES FOR LARGE-SCALE COMBINATORIAL GENETIC SCREENING Researchers at UCSF and the Chan Zuckerberg Biohub have engineered multi-segmented RNA viruses for use in generating large-scale combinatorial libraries. Targeted genetic screening, for example using CRISPR-based systems, is useful to dissect biological pathways....
Published: 5/19/2022   |   Inventor(s): Joseph DeRisi, Hanna Retallack
Keywords(s): Cas9, CRISPR, CRISPRi, Integrated Screening System, Nuclease
Category(s): Technology Classifications > Biology
ENABLING GENETIC ANALYSIS OF DIVERSE BACTERIA WITH MOBILE-CRISPRi
ENABLING GENETIC ANALYSIS OF DIVERSE BACTERIA WITH MOBILE-CRISPRi Researchers at UCSF, funded in part by the Chan Zuckerberg Biohub, have generated a modular and effective CRISPRi system for the genetic dissection of non-model bacteria. The vast majority of bacteria, including human pathogens and microbiome species, lack genetic tools needed to associate...
Published: 11/9/2020   |   Inventor(s): Jason Peters, Carol Gross, Oren Rosenberg
Keywords(s): Bacterial Pathogenesis, CRISPRi, Genetic Dissection, Genome Integration, Non-Model Bacteria
Category(s): Technology Classifications > Biology