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INDUCIBLE VIRAL TRANSDUCTION SYSTEM FOR IN VIVO GENOME MODIFICATION

INDUCIBLE VIRAL TRANSDUCTION SYSTEM FOR IN VIVO GENOME MODIFICATION Researchers at the Chan Zuckerberg Biohub have developed a cellular transduction method for target cell genome modification. Gene therapy, or targeted genome modification, has great potential for biomedicine. There are several genome modification systems available for genome editing,...

Published: 3/17/2023 | Inventor(s): Andrew May, Eleonore Tham, Lucy Maynard, Marco Mignardi, Nicole Paulk, Ryan Leenay

Keywords(s): Adenoviral Vectors, Gene Therapy, Genome Engineering

Category(s): Technology Classifications > Biology

DISCOVERY OF A HIGHLY THERMOSTABLE CAS9 VARIANT

DISCOVERY OF A HIGHLY THERMOSTABLE CAS9 VARIANT Researchers at Stanford and the Chan Zuckerberg Biohub have discovered a Cas9 protein variant from Ignavibacterium that is thermostable at elevated temperatures. The application of genome editing technologies, such as clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated...

Published: 3/17/2023 | Inventor(s): Stephen Quake, Stephanie Schmidt, Feiqiao Yu, Paul Blainey, Andrew May

Keywords(s): Cas9, CRISPR, Genome Editing, Nuclease, Themostable

Category(s): Technology Classifications > Biology