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GENETICALLY ENCODED LYSOSOME TARGETING CHIMERAS FOR CELL-MEDIATED DELIVERY
GENETICALLY ENCODED LYSOSOME TARGETING CHIMERAS FOR CELL-MEDIATED DELIVERY
Researchers at Stanford have developed fully genetically-encodable lysosome-targeting chimeras which allow for the targeted delivery of various proteins into receiver cells.
Lysosome-targeted degradation is an emerging therapeutic modality that facilitates the degradation...
Published: 11/6/2024
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Inventor(s): Jonathan Yang, Carolyn Bertozzi, Alice Ting
Keywords(s): Fusion Protein, Lysosome
Category(s): Technology Classifications > Biology
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METHODS AND COMPOSITION FOR TARGETED RECEPTOR-MEDIATED PROGRAMMABLE MACROMOLECULE DELIVERY
METHODS AND COMPOSITION FOR TARGETED RECEPTOR-MEDIATED PROGRAMMABLE MACROMOLECULE DELIVERY
Researchers at Stanford have developed a novel method for programmable macromolecule delivery via engineered cells, using trogocytosis.
Genome editing technologies have revolutionized the field of personalized medicine. Despite its initial promise, many...
Published: 4/22/2024
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Inventor(s): Lei Qi, Xinyi Chen, Wendy Fantl
Keywords(s): Fusion Protein, Protein Engineering, Trogocytosis
Category(s): Technology Classifications > Biology
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METHODS AND COMPOSITIONS IN PROGRAMMABLE RECEPTOR FOR ANTIGEN DETECTION AND CUSTOMIZED CELL RESPONSES
METHODS AND COMPOSITIONS IN PROGRAMMABLE RECEPTOR FOR ANTIGEN DETECTION AND CUSTOMIZED CELL RESPONSES
Researchers at Stanford have developed new methods to create programmable synthetic receptors (PAGER).
The advent of programmable synthetic receptors represents a new era in cellular therapies and in biomedical science. There are currently tens...
Published: 12/5/2023
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Inventor(s): Nicholas Kalogriopoulos, Alice Ting, Matthew Ravalin, Reika Tei
Keywords(s): Antibody, Fusion Protein, Receptor
Category(s): Technology Classifications > Biology
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CORONAVIRUS NEUTRALIZING COMPOSITIONS AND ASSOCIATED METHODS
CORONAVIRUS NEUTRALIZING COMPOSITIONS AND ASSOCIATED METHODS
Researchers at CZ Biohub SF and Stanford have developed unique fusion proteins that have broad therapeutic benefits for the treatment of infection by existing and future coronaviruses.
Coronaviruses cause human illness ranging from the common cold to more severe diseases. They are large,...
Published: 12/5/2024
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Inventor(s): Payton Weidenbacher, Peter Kim, Eric Waltari
Keywords(s): Antibody, Broad-Spectrum, Coronavirus, Fusion Protein, Highly-Conserved, Inhibitor, Neutralizing, Receptor, Variant
Category(s): Technology Classifications > Biology
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