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GENETICALLY ENCODED LYSOSOME TARGETING CHIMERAS FOR CELL-MEDIATED DELIVERY
GENETICALLY ENCODED LYSOSOME TARGETING CHIMERAS FOR CELL-MEDIATED DELIVERY
Researchers at Stanford have developed fully genetically-encodable lysosome-targeting chimeras which allow for the targeted delivery of various proteins into receiver cells.
Lysosome-targeted degradation is an emerging therapeutic modality that facilitates the degradation...
Published: 11/6/2024
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Inventor(s): Jonathan Yang, Carolyn Bertozzi, Alice Ting
Keywords(s): Fusion Protein, Lysosome
Category(s): Technology Classifications > Biology
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METHODS AND COMPOSITIONS IN PROGRAMMABLE RECEPTOR FOR ANTIGEN DETECTION AND CUSTOMIZED CELL RESPONSES
METHODS AND COMPOSITIONS IN PROGRAMMABLE RECEPTOR FOR ANTIGEN DETECTION AND CUSTOMIZED CELL RESPONSES
Researchers at Stanford have developed new methods to create programmable synthetic receptors (PAGER).
The advent of programmable synthetic receptors represents a new era in cellular therapies and in biomedical science. There are currently tens...
Published: 12/5/2023
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Inventor(s): Nicholas Kalogriopoulos, Alice Ting, Matthew Ravalin, Reika Tei
Keywords(s): Antibody, Fusion Protein, Receptor
Category(s): Technology Classifications > Biology
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LIGHT CONTROLLED PROXIMITY LABELING WITH LOV-TURBO
LIGHT CONTROLLED PROXIMITY LABELING WITH LOV-TURBO
Researchers at Stanford University have developed a new approach for proximity labeling via optogenetic control.
Allosteric regulation is common in naturally occurring enzymes in living tissues. However, despite its ability to improve spatial and temporal control, allostery has yet to be used extensively...
Published: 7/6/2023
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Inventor(s): Joleen Cheah, Alice Ting, Songyi Lee
Keywords(s): Allostery, Enzyme, Optogenetics, Protein Engineering, Proximity Labeling
Category(s): Technology Classifications > Biology
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IMPROVED VARIANTS OF TEV PROTEASE FOR BIOTECHNOLOGICAL APPLICATIONS
IMPROVED VARIANTS OF TEV PROTEASE FOR BIOTECHNOLOGICAL APPLICATIONS
Researchers at Stanford and the Chan Zuckerberg Biohub have developed methods for producing protease variants with increase catalytic efficiency.
Proteases are ubiquitous in biology, and their peptide bond cleavage activities have been harnessed for a wide range of biotechnological...
Published: 3/17/2023
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Inventor(s): Alice Ting, Mateo Sanchez Lopez
Keywords(s): Biosensor System, Integrated Screening System, Protease, TEV
Category(s): Technology Classifications > Biology
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