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METHODS AND COMPOSITION FOR TARGETED RECEPTOR-MEDIATED PROGRAMMABLE MACROMOLECULE DELIVERY

METHODS AND COMPOSITION FOR TARGETED RECEPTOR-MEDIATED PROGRAMMABLE MACROMOLECULE DELIVERY Researchers at Stanford have developed a novel method for programmable macromolecule delivery via engineered cells, using trogocytosis. Genome editing technologies have revolutionized the field of personalized medicine. Despite its initial promise, many...

Published: 4/22/2024 | Inventor(s): Lei Qi, Xinyi Chen, Wendy Fantl

Keywords(s): Fusion Protein, Protein Engineering, Trogocytosis

Category(s): Technology Classifications > Biology

MANIPULATING SPATIAL RNA LOCALIZATION

MANIPULATING SPATIAL RNA LOCALIZATION Researchers at Stanford have developed an inducible and programmable CRISPR-mediated transcript organization (CRISPR-TO) method for repositioning RNAs to various desired subcellular compartments. Spatial RNA transcriptomics, including subcellular mRNA localization, is a core mechanism for spatiotemporal regulation...

Published: 2/14/2024 | Inventor(s): Lei Qi, Mengting Han

Keywords(s): Localization, mRNA, Neuron

Category(s): Technology Classifications > Biology