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­ANTIBODY COMPOSITIONS AND OPTIMIZATION METHODS
­ANTIBODY COMPOSITIONS AND OPTIMIZATION METHODS Researchers at Stanford have invented a method using directed evolution for predicting antibody improved antibody variants. Evolution searches across an immense space of possible sequences for rare mutations that improve fitness. In nature, this search is based on random mutation and recombination,...
Published: 9/14/2023   |   Inventor(s): Brian Hie, Peter Kim
Keywords(s): Antibody, Variant
Category(s): Technology Classifications > Software
MACHINE LEARNING GUIDED DESIGN OF VIRAL VECTOR LIBRARIES
MACHINE LEARNING GUIDED DESIGN OF VIRAL VECTOR LIBRARIES Researchers at UC Berkeley have developed a machine learning model that can aide in the design of more efficient viral vector libraries. Directed evolution of biomolecules to generate large numbers of randomized variants is an important innovation in biochemistry. This methodology can be applied...
Published: 8/17/2023   |   Inventor(s): David Schaffer, Jennifer Listgarten, Danqing Zhu, David Brookes
Keywords(s): Machine Learning, Recombinant Adenoviral-Associated Virus (rAAV), Vector
Category(s): Technology Classifications > Software
DISEASE MANAGEMENT SYSTEM
DISEASE MANAGEMENT SYSTEM Researchers at CZ Biohub SF and Stanford University have developed a new disease management system that enables efficient population-level tracking of disease incidence rates. In recent years, the risk of pandemics has become much more visible to the public. As a result of ongoing international development and our ever-growing...
Published: 11/8/2023   |   Inventor(s): Patrick Arensdorf, Stephen Quake
Keywords(s): Cloud Platform, Infectious Diseases, Low Cost, Population-Level Tracking, Public Health, Self-Collection, Testing Platform
Category(s): Technology Classifications > Software
MADRONE: USER-FRIENDLY BIOINFORMATICS PLATFORM FOR CLUSTER ANALYSIS
MADRONE: USER-FRIENDLY BIOINFORMATICS PLATFORM FOR CLUSTER ANALYSIS Researchers at the Chan Zuckerberg Biohub have developed advanced analytics for pathogen infection tracking and control. Health officials use genomic sequence information for both identification and tracking of infectious disease outbreaks. However, most epidemiological analysis of...
Published: 4/13/2023   |   Inventor(s): David Dynerman, Lucy Li
Keywords(s): Bacterial and Viral Pathogenesis, Epidemiology
Category(s): Technology Classifications > Software