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CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF

CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF Researchers at Stanford have developed compounds that act as potent anti-cancer drugs which selectively inhibit CDK19 over CD8 and promise a greater therapeutic index and reduced systemic toxicity. Breast cancer remains the leading cause of cancer-related death among women worldwide. Patient mortality...

Published: 7/6/2023 | Inventor(s): Vincent Alford, Mark Smith, Michael Clarke, Jitendra Gurjar, Angera Kuo

Keywords(s): CDK19, CDK8, Compound, Selective Inhibition, Therapeutic, Treatment, Triple Negative Breast Cancer

Category(s): Technology Classifications > Biology

CDK19- SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF

CDK19- SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF Researchers at Stanford University have identified new CDK19-selective inhibitors for the treatment of triple negative breast cancer. Breast cancer remains the leading cause of cancer-related mortality among women worldwide. While early cancer detection methods such as genetic biomarker screening...

Published: 3/17/2023 | Inventor(s): Robert Hsieh, Mark Smith, Michael Clarke, Vincent Alford, Andrew Amant

Keywords(s): CDK19, CDK8, Cyclin Dependent Kinases, Kinase Inhibitor, Triple Negative Breast Cancer

Category(s): Technology Classifications > Chemistry