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NOVEL SMALL MOLECULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR
NOVEL SMALL MOLECULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR
Researchers at Stanford University and Washington University have discovered a novel molecular pathway for the treatment of opioid overdose.
Opioids are a powerful tool for pain management when used in clinical care settings. However, in recent years these drugs have...
Published: 9/24/2024
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Inventor(s): Evan Obrien, Kaavya Kumar, Brian Kobilka, Susruta Majumdar, Vipin Rangari
Keywords(s): Opiod, Pain
Category(s): Technology Classifications > Chemistry
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COMPOUNDS AS GABA RECEPTOR MODULATORS
COMPOUNDS AS GABA RECEPTOR MODULATORS
Researchers at UCSF have developed novel GABA-modulating pharmaceutical compounds that are potential therapeutics for the treatment of chronic pain.
Neurotransmitters are the building blocks of information transfer in the central nervous system and can modulate action potentials at the synapses of neurons...
Published: 12/5/2023
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Inventor(s): Matthew McCarroll, Jason Sello, David Kokel, Allan Basbaum, Jarret Weinrich
Keywords(s): Inhibitor, Neuron, Pain
Category(s): Technology Classifications > Biology
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ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR AND CANNABINOID RECEPTOR 1
ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR AND CANNABINOID RECEPTOR 1
Researchers at Stanford have synthesized a potential novel class of pain relief drugs.
Traditional opioids, while highly effective for acute pain management, have historically been prescribed as long-term analgesic treatments despite their well-known addictive properties....
Published: 9/14/2023
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Inventor(s): Evan Obrien, Brian Kobilka, Krishna Kumar
Keywords(s): Analgesic, Opiod, Pain
Category(s): Technology Classifications > Chemistry
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